March 02, 2021
This research builds on earlier work by Herman
Many are still managing with blood droplets on glucose strips, thenusing
self-injection," he said. Those techniques include colloidal nanolithography and
electrohydrodynamic printing, or e-jet, which is somewhat like an inkjet printer
that creates much finer drop sizes and works with biological materials instead
of ink."Even with the contact lens, someone could still manage their diabetes
with self-injection.Their high sensitivity could also measure things such as
pulse rate, oxygen levels, and other aspects of health monitoring that require
precise control. The study appears in the journal Nanoscale. "We can integrate
an array of sensors into the lens and also test for other things: stress
hormones, uric acid, pressure sensing for glaucoma, and things like that," he
said. New York: Diabetes patients may soon be able to monitor their blood sugar
with contact lenses - spelling an end to painful jabs - thanks to scientists who
have developed a transparent sensor.
This research builds on earlier work by
Herman and other OSU engineers that developed a glucose sensor that could be
wrapped around a catheter, such as one used to administer insulin from a
pump.Type 1 diabetes, formerly known as juvenile diabetes, can lead to serious
health complications like retinopathy, blindness, neuropathy, kidney and cardiac
disease, if the glucose level is not carefully controlled. "We have fully
transparent sensors that are working," said Greg Herman, professor at OSU.The
sensor developed by the researchers from Oregon State University (OSU) in the
US, uses a nanostructured transistor that can detect subtle glucose changes in
physiological buffer solutions, such as the tear fluid in eyes. The sensor and
pump would, in effect, act as an artificial pancreas."We can monitor many
compounds in tears and since the sensor is transparent, it doesn't obstruct
vision," said Herman. Researchers in the OSU said the nanostructured transistor
is specifically an amorphous indium gallium oxide field effect transistor (IGZO
FET).
The FET's closely packed, hexagonal, nanostructured network resulted from
complimentary patterning techniques thathave the potential for famous plastic injection machine
manufacturers low-cost fabrication. The sensor could communicate with your
phone to warn you if your glucose was high or low," he said..The sensors they
fabricated using the IGZO FET will be able to transmit real-time glucose
information to a wearable pump that delivers the hormones needed to regulate
blood sugar: insulin and glucagon. "A lot of type 1 diabetics dom not wear a
pump. The transparent FET sensors, might ultimately be used for cancer
detection, by sensing characteristic biomarkers of cancer risk, he said.Such
sensors can detect subtle glucose changes in physiological buffer solutions,
such as the tear fluid in eyes
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