February 25, 2021
Among the many concerns is the issue of microplastics
The proposal, made at the two-day meeting in the central mountain resort of
Karuizawa, would be the first-ever framework to reduce plastic pollution in the
ocean and is expected to be included in a joint communique by the G20 ministers
later Sunday..Tokyo: The Group of 20 major economies was set to seal a deal on
reducing marine plastic waste at a meeting in Japan on Sunday where they also
discussed energy security following the oil tanker attacks in the Gulf of
Oman.Microplastics tend to absorb harmful chemicals and accumulate inside fish,
birds and other animals. The ministers agreed on the importance of securing
stable energy supplies, he said.Many countries, including Japan, have seen
plastic waste pile up in the wake of the ban.
If an international framework on
reducing marine plastic waste is agreed, it would be "the first step toward
resolving the issue," Hiroaki Odachi of Greenpeace Japan told AFP.Japan
"proposed a workable framework" on marine plastic waste that involves emerging
and less developed countries, and was welcomed by member countries, environment
minister Yoshiaki Harada told reporters late Saturday at the G20 environment and
energy ministers&hybrid
injection molding machine39; meeting.Japanese industry minister Hiroshige
Seko, who is co-chairing the discussions with Harada, said late Saturday that
Japan would aim to require businesses to charge for disposable shopping bags by
as early as April to help reduce waste."But given the critical situation of
ocean pollution with plastics, it is urgently needed to set up legally binding
action plans with clear timelines and goals," he added.With only an estimated
nine per cent of plastics ever produced recycled, campaigners say the only
long-term solution to the plastic waste crisis is for companies to make less and
consumers to use less.
Among the many concerns is the issue of microplastics,
the tiny pieces of degraded waste that are difficult to collect once they enter
the water.On energy security, Seko said Tokyo "is watching with grave concerns
at the attacks on oil tankers by someone.Plastic pollution has become an
increasing international concern, particularly after bans imposed by China and
other countries on the import of plastic waste from overseas.Under the expected
agreement, G20 members would commit to undertaking efforts to reduce the amount
of plastic waste that ends up polluting oceans and to reporting their progress
on a regular basis, according to Japanese media.Many countries in the world
already charge for single-use bags or ban them outright.""From a viewpoint of
global energy security, it is necessary for the international community # to
jointly deal with the act," Seko told the meeting
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February 19, 2021
Others are more cautious but investors overall
This is a big, complex molecule, known as a peptide, which would normally be
destroyed by stomach acid and it requires protection with a special compound to
boost absorption.Getting this far with oral GLP is already a notable
achievement, especially after an earlier oral insulin project was abandoned as
uneconomic in 2016. "It will certainly be welcomed by those patients who prefer
to go without their breakfast for half an hour rather than have an injection,â€
said Bailey.LATE BREAKFASTBut oral semaglutide is no plastic injection machine simple
tablet.The once-daily pill belongs to a blockbuster class of treatments known as
GLP-1s that stimulate insulin production, the first of which were derived from
the venomous bite of North America’s Gila monster lizard. "If we get the balance
between the drug’s profile and the drug’s price and market access right then we
can do phenomenally well,†he told Reuters.. But Clifford Bailey, professor of
clinical science at Britain’s Aston University and Dr.LONDON: After nearly a
century building a company worth $125 billion based on injectable drugs,
Denmark’s Novo Nordisk (NOVOb. Rivals, especially Eli Lilly (LLY. Jason Gaglia,
a diabetes expert at the Joslin Diabetes Center in Boston.â€If the data stack up
from 10 pivotal Phase III studies reporting results in 2018, the new drug could
grab more than $5 billion in annual sales, Deutsche Bank analysts believe.
Others are more cautious but investors overall are betting oral and injectable
semaglutide combined will supply around two-thirds of Novo’s revenue growth over
the next five years, according to Thomson Reuters consensus data. "There is
resistance in some patients to move to an injectable medication,†said Dr. So
far, all have been injections.Today, GLP-1s are embraced as a highly effective
diabetes therapy and semaglutide, which was approved as a once-weekly injection
in December, has out-gunned rivals in efficacy.Chief Science Officer Mads
Krogsgaard Thomsen said Novo would pay close attention to such factors as it
tries to reach the three-quarters of diabetics who are not yet on injections.O),
which has a product in early-stage trials.Novo’s oral semaglutide medicine is
important for ensuring the group’s long-term growth - a critical mission after
2017 results last week revealed mounting price pressure in a crowded market
targeting the world’s 450 million diabetics.That represents a life-line for Novo
as it tries to differentiate itself in diabetes at a time when its smaller
biopharma division is also struggling, prompting last month’s abortive attempt
to buy Belgian biotech Ablynx (ABLX.SHUFFLING TREATMENTSDoctors hope oral
semaglutide will provide a new weapon to tackle diabetes earlier with a highly
effective therapy.
Novo’s nearest rival in developing an oral GLP-1 is Israel’s
Oramed (ORMP. Gaglia in Boston said price would be critical in determining its
uptake both among U.†That may be sour grapes by Novo’s arch-rival, whose own
work on developing an oral GLP-1 is only at the preclinical stage.N), are
watching Novo’s final-stage oral semaglutide trials closely, ahead of the drug’s
potential 2020 launch.S. But the needle is still a barrier. Key trials against
Lilly and Boehringer Ingelheim’s pill Jardiance and Merck & Co’s (MRK.But
making patients wait half an hour for breakfast could affect adherence and is a
concern for investors - as is the question of what Novo will charge for a drug
that may perform as well as a pricey injection but looks like rival pills that
cost half as much. insurers and cost-conscious European healthcare systems.
While diabetics with advanced disease need daily insulin shots, those at a less
serious stage start on simple tablets, with GLP-1s added as a potent new option
since 2005. "Once an oral is available I think there will be significant
interest in it.N) Januvia will report later in 2018.Most analysts expect oral
semaglutide to beat these rivals in controlling both blood sugar and weight.
"The highest limit of where we could consider taking the pricing would be
injectable GLP-1 and the lowest level would be somewhere in between current oral
drugs and injectable GLP-1,†Thomsen said.BR). Still, the devil will be in the
details of the 10 Phase III trials, the first of which will deliver results this
quarter. The size of the benefit will feed into Novo’s final pricing decision.If
Novo gets over the pricing hurdle, Bailey and Gaglia believe the new pill is set
to reshuffle treatment regimens, with oral semaglutide being used as a second or
third treatment option after cheap, generic metformin.
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February 02, 2021
Fold in the refined flour and add lemon zest
Fold in the refined flour and add lemon zest. Line the dough in a pie mould, add
1 tbsp of mincemeat mixture into each mould. Take the pastry and divide it into
two equal portions. Allow it to cool down. In a separate bowl, beat eggs and
dissolve instant coffee in water. l In a pan, add pineapple puree, pineapple
chunks and sugar. Bake pies at 180°C for 15-20 minutes until golden brown. Cook
in the preheated oven for 45 to 50 minutes, till the crust gets golden. Mix
cream, butter and sugar. Cool before releasing them from the muffin trays and
dust with icing sugar.Recipe courtesy: chef Pawan Bisht, Junglee BilleeChocolate
marquise pieIngredients Bittersweet chocolate 70 gmHeavy cream 2 cups Butter 2
cups Sweet cream butterUnsweetened cocoa powder 1 cupEgg yolks 6Coffee granules
cup Water 2 tbspWhite sugar 2/3 cupMethodIn a microwave, melt chocolate and stir
until smooth. Remove the plastic wrap and spoon the filling inside the hybrid
injection molding machine two halves. Add cinnamon powder and raisins. Set
aside.Take a plastic bowl and pour all the dry fruits, add orange juice, apple
cubes and spices and mix. Take pie moulds and line them with short crust pastry.
Add brown sugar and melted butter to the mixture. Add flour fold into the
mixture, don’t over mix. Serve. Spoon this mixture in a pie mould and heat.
Garnish with almond flakes and cherry compote. Cream together butter and cocoa
powder. Brush it with honey before serving. Roll in round shapes by placing
between two plastic sheets, and place in buttered pie crust.
Pour brandy in the
end. MethodSift the flour. You may garnish with another cut of star on top of
the pie. Whip the cream until stiff peaks form and fold into the chocolate
mixture. Add eggs and mix at low speed in a mixer. City chefs share some quick
recipes of sweet and savoury pies Mince pie IngredientsFor fillings Red currant
450 gm Raisins 225 gm Sultanas 225 gm Black currant 125 gm Apple, cubed 275 gm
Butter 220 gm Brown sugar 185 gm Mixed spices 5 gm Cinnamon powder 5 gm Brandy
125 ml Lemon peel 125 gm Orange peel 125 gmOrange juice 120 ml For the pie dough
Soft unsalted butter 500 gm Icing sugar 250 gm Eggs 5 Flour 1 kgMethodWhip soft
butter and icing sugar in a bowl to make cream. Re-roll the pastry out and cut 7
cm lids to place on top of the mould and press them on top to seal. Add cocoa
mixture. Add grain sugar and brown sugar and cook the entire mixture. Butter a
pie dish and set aside. Reduce the temperature to 180°C and bake for another 15
to 20 minutes. Make some nice shapes with the leftover pastry. Recipe courtesy:chef Rahis Khan, The Metropolitan Hotel & SpaHomemade pineapple pie
IngredientsMilk for brushing on topSugar 1 tspFor filling: Pineapple, pureed 2
cupLemon juice 1 tspCornflour 2tbspPineapple, finely chopped 1 cup
choppedPineapple essence 1/2 tspSugar 3/4 cup or moreWater 2 tbspMethodPreheat
the oven at 200°C. Add apples and sauté well. Bake this for 30 minutes at 200°C.
Slowly beat in slightly cooled chocolate. Put the mixture in the moulds and
cover with strips of the pastry. Slowly add eggs, one by one.
Keep the mixture
in an airtight container over night at room temperature. Mix till it becomes a
thick jam. Brush the top with milk and sprinkle sugar on top. Using a knife,
stir in just enough of cold water to bind the dough together. Place the dough
into the chiller to set.Recipe courtesy: : chef Vijayant Rawat, Mosaic
HotelsCherry berry pieIngredientsSweet paste baseRefined flour 300 gmButter 200
gmEgg 1Sugar 100 gm Lemon zestCherry fillingButter 100 gmSugar 100 gmEggs
2Cherry 100 gmRum 30 mlFive spices 5 gm Almond flakes 20 gmFlour 100
gmFillingMix all the ingredients and bake in an oven 180°C for 25-30 minutes.
Glaze the mould with rest of the beaten egg, sprinkle caster sugar, then make a
small cut on the top. Use your fingertips to rub the butter into the flour until
you have a mixture that resembles coarse breadcrumbs with no large lumps of
butter remaining.Recipe courtesy: Nidhi Swaroop, home baker. Remove from the
oven and set aside. Add cornflour mixed with water and stir well. Serve when
cold. Brush the edges of each pie with a slightly beaten egg.Xmas spread is
incomplete without the aroma of fresh pies wafting out from the oven. Add in
pineapple essence and lemon juice.Recipe courtesy: chef Sukanta Das, Tamra by
Shangri-La's - Eros HotelApple pieIngredientsFor short crust pastryRefined flour
2 cupsCubed butter 100 gmCold water 1 cupSalt to tasteMethodPut flour and salt
in a large bowl and add butter. Mix dissolved coffee and sugar with egg yolks
until smooth. Cook for 5 minutes.For apple pie Granny smith apple, diced
8Unsalted butter cupGrain sugar cupBrown sugar cupHand full of raisinsCinnamon
powder 1 tspShort crust pastry MethodPreheat the oven at 220°C.
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